2012年2月29日星期三

Blood coagulation analyzer referenced limits and clinical application

Perlong medical equipment company on February 21,-the red blood cells (ESR) subsidence ratio is used to reflect the acute or chronic inflammation, active tuberculosis, rheumatic fever stage, autoimmune diseases, malignant tumor and monitoring the efficacy of treatment the important index, despite the specificity and sensitivity is not very high, but is still considered the acute inflammation is reliable and commonly used detection of the index. At present were still as international standardization of the hematology committee (ICSH) to the recommendations of the party, this law is vulnerable to a variety of factors, along with the rapid development of clinical testing technology, were gradually by some new method, the method of automatic replaced. To judge the dynamic analyzer blood sedimentation performance and effect, the author will this method were compared with the method, the results reported as follows

1, clinical data
1.1 general material choose 380 cases of medical qualified health as control group, and 180 cases were male, female 200 cases). Age 11-80 years old, the average age of 48. Cause the outpatient service 130 patients with as research group, male 70 cases, female 60 cases; Age 15-76 years old, average 52 years old.
1.2 each according to the requirements and methods from 2 tube blood. Were law: in strict accordance with the health ministry of clinical hematology inspection operation write routine. Automatic dynamic blood sedimentation detection: in strict accordance with the automatic dynamic blood sedimentation the operation manual, vacuum extraction 1. 28 mL venous blood (tube 3.8% of folic acid sodium), received specimens were immediately after 2 to 3 times, directly into detection hole through infrared scanned, determine the sample height, and began to analyze, record every 30 min 1, after the experiment to print out 30,60,120 min results, at the same time, the dynamic were hit.
1.3 data processing of SPSS 11. O statistical software, and the comparison of the methodology used linear regression analysis, two methods of measuring results of matching the t test mean differences. In 60 min closed out data and data to adjust for 18 ℃ were reading when the unit, in order to eliminate different temperature on the influence of the test results.

2,Result
2.1 automatic dynamic blood sedimentation of repeatability of random enrol your biometrics is high, medium and low value each a blood, were determined 10 times, the variation coefficient were 3.6%, 2.7% and 2.1%.
2.2 2 groups of two kinds of methods to determine the results more fully automatic control group dynamic assessment of the apparatus used for blood sedimentation (6.88 + /-4.88 mm/h, the variation coefficient was 5.1; The method for assessment were 7.4 + /-5.13 mm/h, the variation coefficient was 6.9. The measured results of the two methods has no significant difference (P = 0.506). Watch [the Numbers] 1008-8849 (2008) 13-2032-01 group automatic dynamic blood sedimentation instrument for the measured results of 35.36 + /-17. 09) mm/h, were the measured results of law for (41.4 + /-17.93 mm/h, the measured results of the two methods has no significant difference (P = 0.486).
2.3 the control group two methods referenced limits the scope of the automatic dynamic blood sedimentation instrument for (5.2 + /-8.9 mm/h, were the scope of the law for (3.9 + /-0.9 mm/h, the measured results of the two methods for matching t test, no significant difference (P = 0.009).

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