2012年2月29日星期三

Perlong medical equipment of nets c-reactive protein function of four

For c-reactive protein research progress faster, at present, it is widely used in the determination of clinical disease early diagnosis and differential diagnosis:
(a) biological characteristics: serum c-reactive protein synthesized by the liver.
(2) And other acute phase of the reactants comparison: clinical most often used to acute phase detection of the index is blood sedimentation (ESR), it can measure the level of indirect fibrin, but the changes in patients and healthy range between large cross, so for the formulation of the results are affected, and it to the reaction of acute inflammation is relatively slow, general 2 ~ 3 genius beginning to rise, although the positive and effective treatment, ESR a few weeks after still don't drop to normal, and at the same time by ESR age, sex, anemia factors. Thus see, ESR whether in or resolve time appear, a c-reactive protein is poor, and by the influence of factors is more.
(3) Method: c-reactive protein determination method of more, the qualitative and quantitative generally fall into two. Including the use of purification of the pneumococcus C-components and patient serum reaction of precipitation, pneumococcal capsule swelling experiment, and specificity of serum and c-reactive protein reaction of precipitation test, the complement of capillary with the test, latex agglutinate experiment, latex diffusion precipitation test and so on, but they sensitivity low. As immune (RIA), radiation fluorescent (FIA), micropalte reader (ELISA) and the development of the method than polluted and the widespread application, people can in a very short period of time accurately measured serum c-reactive protein value. At present are the most widely than turbidity method.
(4) C-reactive protein in the pediatric the clinical application: c-reactive protein is acute phase reaction material, and in the pediatric apply more extensive. Although c-reactive protein concentration change only reflect the disease nonspecific changes, but for clinical disease diagnosis, differential diagnosis and curative effect of observation all have the important reference meanings.

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