Perlong medical equipment nets analyzes creatine kinase isozyme clinical significance

Creatine kinase isozyme divided into: CK-BB, CK-MB, CK-MM the three isozymes. The following is perlong medical equipment nets analyzes creatine kinase isozyme clinical significance:
A, CK-BB (CK1) with mild or moderate brain-damaged patients serum CK-BB evidently higher than those of control value, serum CK-BB on brain damage of the size and the scope of the high and low mortality rate consistent; In cerebrovascular accident and brain surgery, serum CK-BB may also rise. Premature newborn suffocation, if CSFCK-BB rise, more substantial damage occurred brain tissue tip; If CK-BB more than CSF-CF total active 15, is vulnerable to cerebral palsy, intelligence development light obstacles and serious complications.
Second, CK-MB (CK2) serum CK-MB determination of the most important significance lies in the diagnosis of acute myocardial infarction. Acute myocardial infarction chest pain after a 4 ~ 6 hours, the patient serum CK-MB total activity before beginning to rise, 12 ~ 36 hours to spike; More than 72 hours of normal.
Three, CK-MM (CK3) skeletal muscle almost contains only CK-MM, myocardial except CK-MB outside, also the main containing this type isozyme. CK-MM is healthy adults serum CK the main ingredients.
Four, the giant CK (M-CK) adult serum M-CK-I though specific diseases and nothing, but the because of lack of oxygen happened premature suffocation of cerebral palsy or epilepsy for newborn, the serum M-CK-I was sure nerve damage early indicator, the brain is long-term anoxic, release CK-BB in the blood and the result of the Ig polymerization, also have the potential to judge the value of curative effect.




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