2012年3月28日星期三

Perlong Medical equipment of nets about creatine kinase isozyme sort of data

Creatine kinase isozyme is by M and B and composed of unit dimers, form CK-MM (mainly exists in skeletal muscle and myocardial), CK-MB (mainly exists in myocardial) and CK-BB (mainly exists in brain tissue) three isozyme, in addition in the mitochondria exist in a isozymes (CK-MiMi).
CK-MB determination method has two, respectively is CK-MB activity and MB quality.
Reference:
CK-MB activity
10 ~ 24 U/L, cutoff limit (diagnosis limit) : > 25 U/L (immunosuppression a enzyme dynamical method)
< 6% total CK, cutoff limit: > 6% total CK (agarose gel electrophoresis method)
MB quality (maSS)
Male 1.35 ~ 4.94 ng/ml; Cutoff limit: > 5 ng/ml (immune method)
Female 0.97 ~ 2.88 ng/ml; Cutoff limit: > 5 ng/ml (immune method)
CK is by M and B and composed of unit dimers, two different hushais formed three isozyme.
CK-BB (CK1) mainly exist in brain tissue
CK-MB (CK2) mainly exist in the heart muscle
CK-MM (CK3) mainly exist in skeletal muscle tissue
In addition in the mitochondria there is a isozymes (CK-MiMi).
Myocardial different parts CK-MB content is endless also and same, former wall > back wall of right ventricular > left ventricular, so when different parts of the release quantity of MB AMI not only with infarction area, levels, and also the infarct.
CK-MB determination methods: two kinds
The activity: immunosuppression a enzyme dynamical method, agarose gel electrophoresis method.
The quality: immune method

Article: from perlong medical (http://www.pl999.net/)
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